HMG (Menotropins): Dual FSH/LH Gonadotropin in Endocrine Research
HMG (human menopausal gonadotropin, or menotropins) is a gonadotropin preparation that supplies both follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity. It is a classic tool in reproductive-endocrinology research.
Everything below is provided for research context only. This is a laboratory research compound — not a medicine, and nothing here is medical or dosing advice.
What Is HMG?
Where HCG acts mainly like LH, HMG provides both FSH and LH activity, allowing researchers to model the combined gonadotropin signal that drives gonadal function.
Specifications
- Class: gonadotropin preparation (FSH + LH activity), menotropins
- Format: lyophilized powder, reconstituted with bacteriostatic water for research
- Research focus: follicular development, steroidogenesis, reproductive-axis signaling
How HMG Works in Research
- FSH activity: stimulates follicular/germ-cell development pathways.
- LH activity: supports steroidogenesis and, in models, ovulation-type signaling.
- Combined signal: the dual activity makes HMG useful for studying coordinated gonadotropin effects.
Where HMG Sits in Research
HMG is studied alongside HCG to separate FSH-driven from LH-driven effects in the reproductive axis.
Handling in the Lab
- Ships as a lyophilized (freeze-dried) powder; reconstitute with bacteriostatic water using aseptic technique.
- Store the sealed powder cold and dark (long-term at -4°F); once reconstituted keep refrigerated at 36–46°F and use within a short window.
- Minimize freeze-thaw cycles and vial punctures.
- Judge quality by the lot-matched Certificate of Analysis (HPLC purity, mass-spec identity), not the label.
Frequently Asked Questions
What is HMG?
HMG (human menopausal gonadotropin, menotropins) is a gonadotropin preparation with both FSH and LH activity, studied in reproductive-endocrinology research. It is supplied for laboratory research use only.
How is HMG different from HCG?
HMG provides both FSH and LH activity; HCG behaves mainly as an LH-receptor agonist. Researchers use them to model different parts of the gonadotropin signal.
What does HMG contain?
Menotropins supply follicle-stimulating hormone (FSH) and luteinizing hormone (LH) activity.
How is HMG handled in the lab?
It ships as a lyophilized powder, is reconstituted with bacteriostatic water, and is kept cold; judge quality by the lot-matched Certificate of Analysis.
Is HMG approved for human use?
This product is supplied for laboratory research use only — not for human or veterinary use, and nothing here is medical advice.
References
Peer-reviewed research and recognized sources supporting the statements above, provided for research context only — not medical advice.
- Menotropins — prescribing information. DailyMed. View source →
- Human menopausal gonadotropin — reproductive endocrinology. PubMed. View source →
Research-grade HMG — third-party tested, certificate of analysis per lot, same-day US shipping.
Shop research-grade HMG →FOR LABORATORY AND RESEARCH USE ONLY. Golden State Bio supplies research-use-only chemicals for qualified researchers. Not for human or veterinary use; not evaluated by the FDA. Nothing here is medical advice.