Somatropin: Recombinant Human Growth Hormone in Research
Somatropin is recombinant human growth hormone (rhGH) — a 191-amino-acid protein identical in sequence to the growth hormone the pituitary produces. Where GHRH analogs stimulate the body's own GH release, somatropin is the hormone itself.
Everything below is provided for research context only. This is a laboratory research compound — not a medicine, and nothing here is medical or dosing advice.
What Is Somatropin?
Growth hormone is a single-chain protein that acts through the GH receptor to influence growth, cell division, and metabolism, largely by inducing IGF-1.
Specifications
- Class: recombinant human growth hormone (191 aa)
- CAS 12629-01-5
- Format: lyophilized powder, reconstituted with bacteriostatic water for research
- Research focus: GH-receptor signaling, IGF-1 axis, growth and metabolism
How Somatropin Works in Research
- GH receptor: binds and dimerizes the GH receptor, activating JAK/STAT signaling.
- IGF-1: drives hepatic IGF-1 production, the mediator of many downstream growth effects.
- Metabolism: studied for effects on protein, lipid, and glucose metabolism.
Where Somatropin Sits in Research
Somatropin is the direct-hormone counterpart to GH-axis stimulators such as Tesamorelin, CJC-1295, and Ipamorelin.
Handling in the Lab
- Ships as a lyophilized (freeze-dried) powder; reconstitute with bacteriostatic water using aseptic technique.
- Store the sealed powder cold and dark (long-term at -4°F); once reconstituted keep refrigerated at 36–46°F and use within a short window.
- Minimize freeze-thaw cycles and vial punctures.
- Judge quality by the lot-matched Certificate of Analysis (HPLC purity, mass-spec identity), not the label.
Frequently Asked Questions
What is Somatropin?
Somatropin is recombinant human growth hormone (a 191-amino-acid protein) studied for GH-receptor signaling and the IGF-1 axis. It is supplied for laboratory research use only.
How is Somatropin different from CJC-1295 or Tesamorelin?
Somatropin is growth hormone itself; CJC-1295 and tesamorelin are GHRH analogs that stimulate the body's own GH release. One supplies the hormone; the others prompt its secretion.
How does Somatropin work in research?
It binds the GH receptor to activate JAK/STAT signaling and induce IGF-1, influencing growth and metabolism in models. These are research findings, not medical claims.
What is Somatropin's CAS number?
12629-01-5.
Is Somatropin approved for human use?
This product is supplied for laboratory research use only — not for human or veterinary use, and nothing here is medical advice.
References
Peer-reviewed research and recognized sources supporting the statements above, provided for research context only — not medical advice.
- Somatropin (recombinant human growth hormone) — prescribing information. DailyMed. View source →
- Ranke MB, Wit JM. Growth hormone — past, present and future. Nat Rev Endocrinol. View source →
Research-grade Somatropin — third-party tested, certificate of analysis per lot, same-day US shipping.
Shop research-grade Somatropin →FOR LABORATORY AND RESEARCH USE ONLY. Golden State Bio supplies research-use-only chemicals for qualified researchers. Not for human or veterinary use; not evaluated by the FDA. Nothing here is medical advice.