Tesamorelin: The Stabilized GHRH Analog in Growth-Hormone Research
Tesamorelin is a stabilized synthetic analog of growth-hormone-releasing hormone (GHRH). It is studied for its ability to stimulate the pituitary's own release of growth hormone, and it is one of the few peptides in this class with an approved clinical use (for HIV-associated lipodystrophy).
Everything below is provided for research context only. This is a laboratory research compound — not a medicine, and nothing here is medical or dosing advice.
What Is Tesamorelin?
Tesamorelin is based on human GHRH(1-44) with a chemical modification that resists rapid enzymatic breakdown, extending its activity relative to native GHRH.
Specifications
- Class: stabilized GHRH analog
- CAS 218949-48-5
- Format: lyophilized powder, reconstituted with bacteriostatic water for research
- Research focus: GH/IGF-1 axis, visceral-fat metabolism
How Tesamorelin Works in Research
- GHRH receptor: binds the pituitary GHRH receptor to stimulate the body's own pulsatile growth-hormone release, in turn raising IGF-1.
- Stability: the modification slows degradation, giving a longer window of action than native GHRH.
- Metabolic research: studied for effects on visceral adipose tissue and lipid metabolism.
Where Tesamorelin Sits in Research
It is studied alongside other GH-axis compounds such as CJC-1295 and Ipamorelin, which act on complementary pathways.
Handling in the Lab
- Ships as a lyophilized (freeze-dried) powder; reconstitute with bacteriostatic water using aseptic technique.
- Store the sealed powder cold and dark (long-term at -4°F); once reconstituted keep refrigerated at 36–46°F and use within a short window.
- Minimize freeze-thaw cycles and vial punctures.
- Judge quality by the lot-matched Certificate of Analysis (HPLC purity, mass-spec identity), not the label.
Frequently Asked Questions
What is Tesamorelin?
Tesamorelin is a stabilized synthetic analog of growth-hormone-releasing hormone (GHRH), studied for stimulating the body's own growth-hormone release. It is supplied for laboratory research use only.
How does Tesamorelin work?
It binds the pituitary GHRH receptor to stimulate pulsatile growth-hormone release, which raises IGF-1. A chemical modification slows its breakdown for a longer window of action. These are research findings, not medical claims.
How is Tesamorelin different from CJC-1295?
Both are GHRH analogs, but they differ in structure and duration. Tesamorelin is based on GHRH(1-44) with a stabilizing modification; CJC-1295 is a separate GHRH analog often studied with ghrelin-receptor agonists like ipamorelin.
What is Tesamorelin's CAS number?
218949-48-5.
Is Tesamorelin approved for human use?
The research compound sold here is for laboratory use only. Although tesamorelin has an approved clinical use for a specific condition, this product is not a medicine and nothing here is medical advice.
References
Peer-reviewed research and recognized sources supporting the statements above, provided for research context only — not medical advice.
- Falutz J, et al. Tesamorelin, a GHRH analogue, in patients with HIV-associated lipodystrophy. N Engl J Med. View source →
- Tesamorelin — FDA prescribing information. DailyMed. View source →
Research-grade Tesamorelin — third-party tested, certificate of analysis per lot, same-day US shipping.
Shop research-grade Tesamorelin →FOR LABORATORY AND RESEARCH USE ONLY. Golden State Bio supplies research-use-only chemicals for qualified researchers. Not for human or veterinary use; not evaluated by the FDA. Nothing here is medical advice.